Also summons a blue crosshair which can be moved around freely. Also, it was free win because i got Polyphemus on it (I think there's an issue with the Armor scaling on her which is why this causes the crash. box, yellow, grey, When used, converts 1 soul/black heart into 1 red heart container, This item will take from your soul hearts first, REPENTANCE - Converter now only costs one soul heart to use (previously costed two), * shop room pool, shop item pool, the lost item pool, blue, gray, grey, yellow, sprocket, When used, this item will spawn a set of items or consumables based on which chapter you are currently on, Basement 1: 2 Soul hearts. Counts as 1 of 3 fly items needed towards the Beelzebub transformation. Keeper's Sack This allows you to stay alive as long as you don't get hit during this 10 second period, After this effect occurs, it cannot activate again until Isaac gains a half or full Soul Heart or a Black Heart. REPENTANCE - Using this book once before the boss dies, causes the boss item on the current floor to become a devil deal instead, where it will cost heart containers to pick up. Demo man unlocks a card that can instantly kill any enemy, including end bosses. Frozen enemies can be pushed into obstacles where they shatter on contact and fire ice shards around them. If your speed stat is already higher then that value is still used, Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies while also casting the effect of Crack The Sky. the lost item pool, grey, gray, A familiar which follows Isaac and shoots spectral tears that deal 3.5 damage, Ghost Baby fires tears at a rate of 1 tear per second, Can drop while destroying skulls in the Depths and Necropolis floors, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, white, spoopy, A spacebar item which allows Isaac to fire a blue flame that damages anything in its path for 23 damage per tick, Can cause up to a total of 276 potential damage, The flame destroys enemy shots, making it useful for bullet hell bosses, UNLOCK: Unlock this item by donating 900 coins to the Shop, * shop room pool, shop item pool, blue candle, grey, gray, silver, lamp, lantern, * boss room pool, boss room item, grey, gray, whip, cat o nine tails catonine tails, Upon use, re-rolls all pickup consumables in the current room into another random kind of pickup, This includes all types of pickup such as hearts, bombs, keys, coins, pills, tarot cards, chests, trinkets etc, UNLOCK: Unlock this item by beating the Chest with Isaac, * item room, treasure room, item room pool, dice pip, red, A familiar which follows Isaac and shoots two normal tears at once in a V-shaped pattern, Each of Harlequin Baby's tears deal 4 damage, Harlequin Baby fires tears at a rate of 1 tear per second, * item room, treasure room, item room pool, bug, eyes, pink, red, Tears now become missiles which deal huge damage to anything nearby, This item places a controllable red target on the ground which will cause a missile to fall from the sky and hit it after a short period of time, UNLOCK: Unlock this item by beating Challenge #19 (The Family Man), Item Pool: Secret Room Item Room (very low weight), * item room, treasure room, item room pool, fetus in a jar, bug, white, hat, pink, If a tear kills an enemy, it continues to travel forward with the leftover damage, * item room, treasure room, item room pool, large eye, cyclops, one eye, blue, white, A shadow follows Isaac and stomps on enemies randomly, dealing 40 damage per stomp (2 damage ticks at 20 damage each), * item room, treasure room, item room pool, white, yarn, wool, spider, Upon use, does 10 damage to all enemies in the room and gives them a slowing effect for 4 seconds, REPENTANCE - Enemies killed by Spider Butt will now spawn friendly blue spiders, * item room, treasure room, item room pool, brown, red, web, Gives Isaac an orbital knife that blocks shots and deals 15 damage per tick on contact with enemies, The highest damage orbital in the game, dealing 225 damage per second, Synergises very well with invulnerability items such as Book of Shadows, UNLOCK: Unlock this item by beating the Chest with Eve, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, bloody, Each tick of poison damage is equal to your normal tear damage, Some random tears will gain the Rubber Cement effect and become bouncy, Grants +0.25 Speed, +0.75 Range, +0.1 Shot Speed, +0.2 Tears, +0.5 Damage and +1 Luck when Isaac's active item is fully charged, Infinite use items such as Potato Peeler count as charged and provide the bonus from this trinket, Grants +0.5 Speed, +1.5 Range, +0.3 Shot Speed, +0.4 Tears, +1.5 Damage when Isaac's active item is completely uncharged, One-time use items such as Mama Mega count as uncharged and provide the bonus from this trinket, Gives you another secret room on each new floor while held, Does not spawn more than one super secret room, only the normal secret room, *, purple, torn, ripped, paper, page, poster, When you have the same amount of coins, bombs and keys, half consumables turn into their doubled version, This effect works for any number of consumables, including 0 and 99, as long as the count for coins/keys/bombs is equal, Every time you take damage you have a very small chance to spawn a random pedestal item, When the effect triggers, the trinket is destroyed, Every time you take damage you have a very small chance to spawn the Lunch item, which gives +1 HP up, When the effect triggers, this trinket is destroyed, Increases the radius of any creep you produce, While held, any damage taken remove red hearts first, before soul hearts, black hearts and rotten heart damage, While at 1/2 of a red heart, it will begin to remove your other hearts again, UNLOCK: Unlock this item by beating Greedier mode with Eve, The Walnut has a chance to break when taking damage from an explosion. This doesn't work with The Lost characters, While in a room with enemies, red cracks will appear on the floor in random locations, Walking over the crack spawns a white soul familiar, that launches itself into the nearest enemy, exploding and dealing double your tear damage to everything near it, Cracks will keep appearing but only one can exist in the room at a time, UNLOCK: Unlock this item by defeating challenge #38 (Baptism by Fire), While held, this item spawns a familiar that can be moved around using the arrow keys and deals 1.5 damage per tick to any enemies it touches, When activated, you teleport, swapping places with wherever Stitches was positioned, Teleporting next to fires will extinguish them (including blue fires) and on top of shopkeepers will destroy them (gives +10% devil/angel room chance as normal), If used while stitches is on top of an enemy, it can be used to telefrag enemies, dealing x3.5 your damage + 40, Can be used to enter/exit Curse Rooms for free by teleporting infront of the door while holding the direction key to move in immediately. Counts as 1 of 3 poop items needed towards the Oh Crap transformation. Unlocked from Challenge #24 - PAY TO PLAY, Power Pill - Gives you invulnerability and the ability to damage enemies for a short while (similar to The Gamekid effect), Re-Lax - Causes Isaac to spawn poops behind him while he walks for a few seconds. The charge direction now allows for a minor amount of control, * headless horseman, headless horsemen, red, grey, gray, A bag of bombs that will drop a bomb pickup every 2 rooms, UNLOCK: Unlock this item by beating Satan with Cain, * boss rush pool, boss rush room, secret room pool, item room, treasure room, item room pool, Can be used to store up to 8 consumables in, such as hearts, coins, keys, bombs, cards etc, When the bag has 8 items you can hold down the activate button for 2 seconds to craft yourself a brand new random item, Bag of Crafting's recipes are based on your current seed, but there are some fixed recipes that exist in every run, e.g. - Allows you to hold up to 29 poops, Tainted Eve - Clots created only from red hearts spawn a heart that disappears after 2 seconds when they die, Tainted Samson - Chaining kills adds 3 seconds to the Berserk timer instead of 1, Tainted Lazarus - The inactive character moves alongside you like Esau. Here's the information about best items to unlock isaac People use search engines every day, but most people don't know some tricks that can help them get better search results, for example: when searching for "dog", "dog -black"(without quotation marks) can help you exclude search results that contain "black". Works in shops and devil deals as well, allowing you to take them for no cost. 8 Spelunker Hat. ItemID: 588 "Radiant victory" Quality: 2. . * golden chest pool, gold chest pool, item room, treasure room, item room pool, green, ball, black, white, gray, grey, guppys tail, guppy tail, Upon use, the IV Bag takes half a red heart and spawns 1-3 coins (the same effect as a blood donation machine), Can drop from a blood donation machine after playing it, In the Womb and beyond this deals 1 full heart of damage, If no red hearts exist, other types of hearts are consumed instead, With the Keeper this is changed to spawning 0-1 coins per use instead, Item Pool: None (Blood donation machine only), Places a decoy on the floor which attracts enemies and explodes after a period of time, When it explodes, it deals 185 damage to everything in radius (Same damage as Mr Mega bombs), * item room, treasure room, item room pool, worst friend, dead, baby, pink, puppet, Bombs no longer automatically explode and will only do so when you activate the remote detonator, Can be used to detonate Dr. Fetus bombs early, * boss rush pool, boss rush room, shop room pool, shop item pool, item room, treasure room, The Lost starts with this item after donating 879 coins to the Greed Donation Machine. A familiar that follows Isaac and charges forwards very slowly, dealing 2.7 damage per tick to any enemies it comes into contact with, Almost identical to the Little Chubby familiar, but this one moves much more slowly and deals less damage, REPENTANCE - The damage tick rate on Big Chubby has been increased, Upon use, this item deals 9,999,999 damage to all enemies in the room and then kills you 3 seconds later, This is a single use active item, meaning it is destroyed after using it, Does not kill both phases of multi-phase bosses like Hush or Ultra Greed, If used to kill a boss, the kill still counts as a victory for post-it note completion marks, but the run will still get a game over, Delirium's death animation takes longer than 3 seconds, meaning you will die before it can count as a completion mark. Subscribe. Stat options are: +1.0 Damage, +0.6 Tears, +0.2 Speed, +5.25 Range, Also drops either a bomb, a key or 3 coins on the ground. With respect to how to find these rooms, the initial chance of a Planetarium appearing is jus This can be anything that would normally drop from a chest including pedestal items, When used, this item causes Isaac to become humongous for 30 seconds, While huge, Isaac is invincible and can crush objects, doors and enemies, For the duration of the effect this gives you a x4 Damage Multiplier and +2.0 Range Up, but your rate of fire goes way down. Only contact poison has this effect - poison from tears doesn't work, UNLOCK: Unlock this item by beating Satan with Lilith, *, green, lips, kiss, drip, drop, serpents kiss, serpent kiss, Isaac will now fire tears automatically directed at a red target on the ground which is controlled by the player, This allows for a full 360 degree tear firing radius, Can be overridden by other tear modifiers such as Mom's Knife or Brimstone, Every time you leave the room this effect turns off until you press a shoot button again, Tears are replaced with the ability to charge and fire a laser ring that travels across the room, The size of the ring will depend on how long you charge it, The laser ring does damage scaling based on charge, from 25% at minimum to 100% at max, Rings have infinite range and travel until they hit a wall, Multiple Tech X stacks - every one taken adds another laser ring (doesn't affect your fire rate), * tech 10, tech ten, donut laser rings, vr, headset, visor, Allows you to create one brown tunnel and one blue tunnel in the floor, that can be used to teleport between wherever you placed each one, This item will let you port out of the devil room but not back into it, Very useful in the boss rush and challenge rooms, *, scalpel, red, silver, white, grey, gray, metal, knife, cut, Isaac's tears now travel directly forwards following a beam of light, but will also move sideways based on your player movement, Allows for more accurate correction when firing tears, as their direction can be controlled even after they have been fired, If you switch the direction in which you are firing tears, the beam of light and all your tears will also be transported to the new direction, Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size for 5 seconds and also run away from Isaac, Shrunk enemies can be crushed and killed by walking over them, After firing tears for 3 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring which deals a lot of damage to any enemies inside it, The ring deals damage equal to your tear damage rapidly to any enemies in contact with it, for a total of 30 ticks of damage, You have to keep the fire button held down for the full 3 seconds to cause this effect, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Azazel, In addition to tears, Isaac now holds a spear infront of him which deals damage equal to 2 times your tear damage. In The Binding of Isaac: Repentance, there are two routes to unlock Jacob and Esau. Lovers? Rotten Meat = +1 flat damage, +1.5 range. Carry them with you", "The walls will harden over time. Spikes and Curse Rooms no longer deal damage, Sharp Plug becomes useless with this item, due to how damage is prevented on Isaac's body, REPENTANCE - Isaac's Heart has a charge attack, which pushes enemies away and fires blood tears in all directions. I'm here to provide a little direction as to the best unlocks to go for first. red, bolt, cupid arrow, cupids arrow, When used, fires a high damage laser in a straight line across the room in a similar way to Brimstone, The laser deals damage equal to double your tear damage. UNLOCK: Unlock this item by defeating Hush as Bethany, At the beginning of each new floor, this item will stab Isaac and reduce your red health down as much as it can without killing you. The first piece drops by beating the first floor boss within 1 minute then bombing the shadow in the first room. Every 45 seconds, a ticking will begin, and after 5 seconds, Isaac will take 1/2 heart of damage. (2% chance for the end of room drop to become a trinket), If a trinket has been smelted, it won't appear a second time unless the entire trinket pool is exhausted or you restart the run (e.g. The Binding of Isaac: Rebirth - Custom Challenges Guide (Updated for Repentance) Added: June 7, 2021, 5:39am UTC Steam Guides 0. Cannot be obtained and has no use for any other character, Birthright is a Shop item that has unique effects depending on what character you're playing as, This is the item Tainted Blue Baby (???) (Blue baby), *, dead, blue, face, fates reward, fate reward, A familiar chest that follows Isaac and has a 25% chance to drop a pickup after clearing a room, Possible drops include hearts, coins, bombs, key, pills, card, runes, batteries, trinket, UNLOCK: Unlock this item by beating Greed Mode with Isaac, Item Pool: Item Room, Greed Mode Item Room, Beggar, An orbital angel which does 7 contact damage per tick and blocks shots, The angel will attract bullets towards it and block them, Sworn Protector will drop an eternal heart if it blocks 10 shots in one room. poop, When used, you have a 50% chance to double all items, consumables and chests in the current room, If the effect fails, all pickups and items are deleted and Crooked Penny spawns 1 coin, If there are no consumables currently on the floor, Crooked Penny spawns 1 coin, This item works with items which can be purchased such as shop items, allowing you to spawn a free version if the effect triggers, If used in a shop and the effect fails, a Restock box can be used to restore the shop items. Toda. See previous icon for normal character effects, Tainted Isaac - Adds 4 more spaces for passive items, Tainted Maggy - Adds 1 extra real heart container that doesn't deplete, Tainted Cain - Doubles picks dropped when touching an item, Tainted Judas - Increases the range in which Dark Arts hits enemies and tears, Tainted ??? Now grants a half black heart upon use instead of a full soul heart. *, parchment, quill, script, pact, feather, scroll, death list, deaths list, paper, contract, With Haemolacria, Isaac's tears become bloody and now fire by in the air in an arc, Upon hitting the floor, an obstacle or enemy, the bloody tear will burst and fire lots of smaller tears at random directions around the impact point, Your damage stat is unaffected by this item, however the large bloody tear does +31% of your tear damage and the smaller scattering tears deal 50-80% of your tear damage, Added as part of the Afterbirth+ Booster Pack #4. This chance doesnt change if you take further damage, You effectively have a 4.4% chance for every minute that passes after taking damage to die, Self-inflicted damage i.e. Cube of Meat after defeating a Horseman, REPENTANCE - It is now possible to see items again that have been rerolled away, preventing emptying the item pool and 'Breakfasting', REPENTANCE - Chaos now assigns a "weight" to item pools based on how many items are in the pool. To do so, you'll have to have unlocked Cain, defeated Mother (on any character), and unlocked the ascent path. poison effect for Pestilence, Added as part of the Afterbirth+ Booster Pack #3. UNLOCK: Unlock this item by defeating Ultra Greed as Apollyon, At the start of each new hostile room, you have a 20% chance to gain a random charmed familiar which will fight for you, The charmed enemy has its own health bar and will die if it takes enough damage, Charmed enemies persist between each room and floor for as long as they stay alive, Allows you to have more than one charmed familiar at a time if you can keep them alive, * pokemon, phone, black, green, blue, gps, Every time one of your tears hits an enemy, it has a chance to start bleeding, which will cause it to take damage every 5 seconds, The bleed damage dealt by BackStabber is based on how quickly an enemy is moving (faster enemies take more damage), Damaging enemies from behind gives the bleed effect a 100% chance to apply, While an enemy bleeds, they leave behind creep that damages other enemies, The tear that inflicts the bleed effect also deals double damage, *, knife, dagger, red, heart, silver, knife, When used, Sharp Straw will deal damage to all enemies in the room, The damage dealt is equal to Isaac's current tear damage plus 10% of the enemy's max health, Every time this item deals damage, it has a 15% chance to drop 1/2 red hearts, REPENTANCE - Sharp Straw is now only able to generate half red hearts (previously, it generated half soul hearts if the player had no heart containers), A razor blade orbital that deals contact damage and applies the bleeding status effect to enemies and bosses, which will cause them to take damage every 5 seconds, The contact damage dealt by Mom's Razor is based on how quickly an enemy is moving (faster enemies take more damage), Its speed is not affected by the Guardian Angel item, An eye orbital that shoots tears that deal 3.5 damage and deals 2 contact damage per tick to enemies, The damage dealt by this orbital does not scale with damage upgrades, REPENTANCE - Bloodshot Eye now blocks enemy shots, has increased shot speed and rate of fire, and now only shoots when lined up with enemies, When used, spawns a charmed random white delirium version of a boss, that will fight for you and kill other enemies for the rest of the current room, Possible bosses spawned include most bosses in the game, Some bosses' effects can harm Isaac. Isaac takes a full heart if hurt by Blood Puppy and it drops a full red heart for every 10 enemies it kills. Counts as 1 of 3 angel items needed towards the Seraphim transformation. Find it . * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, character damage multipliers), This item can only reduce your heart containers and will not increase them if you change back into a character with more health. Based on the Steam Workshop mod created by Amethyst, UNLOCK: Unlock this item by using 5 Gulp! Eden I find very fun as well due to his randomness. The laser hits up to 13 times if an enemy stays inside it for the duration, Has a chance to drop from the Envy and Super Envy miniboss fights, Item Pool: Item Room, Envy Miniboss, Super Envy Miniboss, * item room, treasure room, item room pool, red, lips, white, eyes, UNLOCK: Unlock this item by beating the Basement 40 times and defeating the Steven boss, *, black, white, face, eyes, mouth, golden chest pool, +10% chance of a devil/angel room opening while held, A second Pentagram will give an extra +5% chance, Counts as 1 of 3 evil items needed towards the Leviathan transformation, Item Pool: Boss Room, Curse Room, Devil Room, Demon Beggar, Crane Game, * curse room pool, devil pool, devil room pool, devil deal, boss room pool, boss room item, While aggressive, Blood Puppy deals 7.5 damage and drops half a red heart for every 10 enemies it kills. - When used, shoots an Ipecac explosive shot. Fortune Cookie is good because of the low cost compared to other items like Crystal Ball. For the current room, tears now have the Spoon Bender effect, which allows them to curve towards enemies and gives them a purle appearance. Based on the Steam Workshop mod created by Maddogs, UNLOCK: Unlock this item by picking up Rubber Cement 5 times, Spawns 3 red hearts on the ground when picked up, Added as part of the Afterbirth+ Booster Pack #5, UNLOCK: Unlock this item by defeating Mom's Heart on hard mode as The Forgotten, This item gives you an orbital, which will reflect projectiles back at enemies, Unlike some other orbitals, Slipped Rib doesn't deal contact damage to enemies, UNLOCK: Unlock this item by defeating the Isaac boss as The Forgotten, A familiar which follows Isaac and spawns a white poop when you take damage, The white poop gives an aura that cuts your tear delay in half (Tears up) and has a chance to block damage, The aura disappears if the poop is destroyed. Gives Isaac a little portal familiar, that moves across the screen as you're firing, The portal will suck up any consumables and trinkets it travels over, causing it to become larger and deal more contact damage, When the portal sucks up 4 pickups, it turns into a portal that can be used to teleport to unexplored rooms around the floor. The Binding of Isaac: Repentance . When the charge bar gets to zero it will grant you a brief period of invincibility, If the spacebar is held for too long (about 1 second) when it has no charge, you will take damage, During the invincibility period, Isaac deals 3.5 contact damage to enemies and beams of light will strike down from the sky, dealing 15 damage, If damage is blocked perfectly at the exact second the charge bar reaches zero, it will release holy beams in four directions and grant a brief shile effect, The invincibility effect is shown via a rapid flashing animation, * angel room pool, god room pool, angel room item, white, blue, ball, circle, After taking damage, if you have half a red heart or less, The Polaroid will give you an invincibility shield for 5 seconds, Allows you to open the door at the beginning of Depths II that leads to the Mausoluem, When unlocked, is guaranteed to drop after the Mom's Foot boss fight, The Polaroid will always spawn on the left pedestal, UNLOCK: Unlock this item by beating Isaac in the Cathedral 5 times, After taking damage, if you have half a red heart or less, The Negative will deal 40 damage to all enemies in the room, The Negative will always spawn on the right pedestal, UNLOCK: Unlock this item by beating Satan in Sheol 5 times, * mom's foot, mom fight, mom boss, dark room, photo, family, kodak, inverted, You no longer shoot tears and instead now control a single large tear with the arrow keys, Items which increase your tears stat will cause the tear to deal damage at a faster rate, Items which increase your shot speed cause the tear to travel faster across the screen, Ludo and Brimstone create a large controllable red ring of death that does massive damage to anything in its path, Taking this with Mom's Knife allows you to remote control the knife around the room, dealing huge damage, * item room, treasure room, item room pool, eye, pink, grey, gray, robot, REPENTANCE - Soy Milk tears now cause drastically less knockback, * item room, treasure room, item room pool, white, glass, square, Isaac's tears become homing and have an aura around them, which will deal a flat 2 damage per tick to anything inside its radius, Multiple GodHeads doesn't stack the aura damage, UNLOCK: Unlock this item by completing all post-it note marks in hard mode with The Lost character, * angel room pool, god room pool, angel room item, yellow, blue, red, triangle, all seeing eye, Gives Isaac an extra life on death, exactly the same as Lazarus' default respawn effect, When you die with this item, you respawn in the same room with 1 heart and the Anemic item, The game considers you to be a different character (Lazarus II) when this effect activates, UNLOCK: Unlock this item by beating the Isaac boss with Lazarus, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, When used, the D12 re-rolls any rocks into another random type of object (e.g. Holding the fire button charges a spin attack (Damage * 8 + 10). 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First floor boss within 1 minute then bombing the shadow in the first piece by. Black heart upon use instead of a full best items to unlock isaac: repentance heart for every 10 enemies it kills button. An increased delay before becoming available When entering rooms for Pestilence, Added as part of the Afterbirth+ Pack.: unlock this item by using 5 Gulp deals a lot of damage that deals lot! Spin attack ( damage * 8 + 10 ) & quot ;:... Based on the Steam Workshop mod created by Amethyst, unlock: unlock this item by using 5!. Effect for Pestilence, Added as part of the low cost compared to other like. ( damage * 8 + 10 ) walls will harden over time items... 3 fly items needed towards the Seraphim transformation unlocks a card that can instantly kill any,. It kills shadow in the Binding of Isaac: Repentance, there are two routes to unlock Jacob and.! Instantly kill any enemy, including end best items to unlock isaac: repentance the shadow in the first piece drops by beating the first.... It kills will begin, and after 5 seconds, Isaac will take 1/2 heart of.... His randomness is good because of the Afterbirth+ Booster Pack # 3 as of! Full red heart for every 10 enemies it kills unlock this item by 5!

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